Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation

Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the specific mechanisms of PRMT activity in splicing regul...

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Detalles Bibliográficos
Autores principales: Maron, Maxim I, Casill, Alyssa D, Gupta, Varun, Roth, Jacob S, Sidoli, Simone, Query, Charles C, Gamble, Matthew J, Shechter, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765754/
https://www.ncbi.nlm.nih.gov/pubmed/34984976
http://dx.doi.org/10.7554/eLife.72867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765754/
https://www.ncbi.nlm.nih.gov/pubmed/34984976
http://dx.doi.org/10.7554/eLife.72867

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