PRC1 sustains the integrity of neural fate in the absence of PRC2 function

Polycomb repressive complexes (PRCs) 1 and 2 maintain stable cellular memories of early fate decisions by establishing heritable patterns of gene repression. PRCs repress transcription through histone modifications and chromatin compaction, but their roles in neuronal subtype diversification are poo...

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Detalles Bibliográficos
Autores principales: Sawai, Ayana, Pfennig, Sarah, Bulajić, Milica, Miller, Alexander, Khodadadi-Jamayran, Alireza, Mazzoni, Esteban O, Dasen, Jeremy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765755/
https://www.ncbi.nlm.nih.gov/pubmed/34994686
http://dx.doi.org/10.7554/eLife.72769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765755/
https://www.ncbi.nlm.nih.gov/pubmed/34994686
http://dx.doi.org/10.7554/eLife.72769

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