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PRC1 sustains the integrity of neural fate in the absence of PRC2 function
Polycomb repressive complexes (PRCs) 1 and 2 maintain stable cellular memories of early fate decisions by establishing heritable patterns of gene repression. PRCs repress transcription through histone modifications and chromatin compaction, but their roles in neuronal subtype diversification are poo...
Autores principales: | Sawai, Ayana, Pfennig, Sarah, Bulajić, Milica, Miller, Alexander, Khodadadi-Jamayran, Alireza, Mazzoni, Esteban O, Dasen, Jeremy S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8765755/ https://www.ncbi.nlm.nih.gov/pubmed/34994686 http://dx.doi.org/10.7554/eLife.72769 |
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