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Cyclic RGD-Decorated Liposomal Gossypol AT-101 Targeting for Enhanced Antitumor Effect

INTRODUCTION: (-)-Gossypol (AT-101), the (-)-enantiomer of the natural compound gossypol, has shown significant inhibitory effects on various types of cancers such as osteosarcoma, myeloma, glioma, lung cancer, and prostate cancer. However, the clinical application of (-)-gossypol was often hindered...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Zhang, Ruirui, Zhang, Dan, Zhang, Chun, Zhang, Zhuo, Fu, Xiujuan, Luo, Yu, Chen, Siwei, Wu, Ailing, Zeng, Weiling, Qu, Kunyan, Zhang, Hao, Wang, Sijiao, Shi, Houyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766252/
https://www.ncbi.nlm.nih.gov/pubmed/35068931
http://dx.doi.org/10.2147/IJN.S341824