Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice

Proteolytic activation of the epithelial sodium channel (ENaC) by aberrantly filtered serine proteases is thought to contribute to renal sodium retention in nephrotic syndrome. However, the identity of the responsible proteases remains elusive. This study evaluated factor VII activating protease (FS...

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Detalles Bibliográficos
Autores principales: Artunc, Ferruh, Bohnert, Bernhard N., Schneider, Jonas C., Staudner, Tobias, Sure, Florian, Ilyaskin, Alexandr V., Wörn, Matthias, Essigke, Daniel, Janessa, Andrea, Nielsen, Nis V., Birkenfeld, Andreas L., Etscheid, Michael, Haerteis, Silke, Korbmacher, Christoph, Kanse, Sandip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766372/
https://www.ncbi.nlm.nih.gov/pubmed/34870751
http://dx.doi.org/10.1007/s00424-021-02639-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766372/
https://www.ncbi.nlm.nih.gov/pubmed/34870751
http://dx.doi.org/10.1007/s00424-021-02639-7

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