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Quantifying protein abundance on single cells using split-pool sequencing on DNA-barcoded antibodies for diagnostic applications

Proteins play critical roles across all facets of biology, with their abundance frequently used as markers of cell identity and state. The most popular method for detecting proteins on single cells, flow cytometry, is limited by considerations of fluorescent spectral overlap. While mass cytometry (C...

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Detalles Bibliográficos
Autores principales: Sheng, Jenny, Hod, Eldad A., Vlad, George, Chavez, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766443/
https://www.ncbi.nlm.nih.gov/pubmed/35042926
http://dx.doi.org/10.1038/s41598-022-04842-7