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Quantifying protein abundance on single cells using split-pool sequencing on DNA-barcoded antibodies for diagnostic applications
Proteins play critical roles across all facets of biology, with their abundance frequently used as markers of cell identity and state. The most popular method for detecting proteins on single cells, flow cytometry, is limited by considerations of fluorescent spectral overlap. While mass cytometry (C...
Autores principales: | Sheng, Jenny, Hod, Eldad A., Vlad, George, Chavez, Alejandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766443/ https://www.ncbi.nlm.nih.gov/pubmed/35042926 http://dx.doi.org/10.1038/s41598-022-04842-7 |
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