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Machine learning assisted real-time deformability cytometry of CD34+ cells allows to identify patients with myelodysplastic syndromes

Diagnosis of myelodysplastic syndrome (MDS) mainly relies on a manual assessment of the peripheral blood and bone marrow cell morphology. The WHO guidelines suggest a visual screening of 200 to 500 cells which inevitably turns the assessor blind to rare cell populations and leads to low reproducibil...

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Detalles Bibliográficos
Autores principales: Herbig, Maik, Jacobi, Angela, Wobus, Manja, Weidner, Heike, Mies, Anna, Kräter, Martin, Otto, Oliver, Thiede, Christian, Weickert, Marie‑Theresa, Götze, Katharina S., Rauner, Martina, Hofbauer, Lorenz C., Bornhäuser, Martin, Guck, Jochen, Ader, Marius, Platzbecker, Uwe, Balaian, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766444/
https://www.ncbi.nlm.nih.gov/pubmed/35042906
http://dx.doi.org/10.1038/s41598-022-04939-z