Responsiveness of PNPLA3 and lipid-related transcription factors is dependent upon fatty acid profile in primary bovine hepatocytes

Knockdown of patatin-like phospholipase domain-containing protein 3 (PNPLA3) increased triglycerides (TG) in primary bovine hepatocytes, suggesting that PNPLA3 plays a causal role in hepatic TG clearing. In vivo, PNPLA3 abundance across the periparturient period is inversely related to hepatic TG ac...

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Detalles Bibliográficos
Autores principales: Erb, Sophia J., Chandler, Tawny L., White, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766451/
https://www.ncbi.nlm.nih.gov/pubmed/35042927
http://dx.doi.org/10.1038/s41598-021-04755-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766451/
https://www.ncbi.nlm.nih.gov/pubmed/35042927
http://dx.doi.org/10.1038/s41598-021-04755-x

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