Cargando…
Responsiveness of PNPLA3 and lipid-related transcription factors is dependent upon fatty acid profile in primary bovine hepatocytes
Knockdown of patatin-like phospholipase domain-containing protein 3 (PNPLA3) increased triglycerides (TG) in primary bovine hepatocytes, suggesting that PNPLA3 plays a causal role in hepatic TG clearing. In vivo, PNPLA3 abundance across the periparturient period is inversely related to hepatic TG ac...
Autores principales: | Erb, Sophia J., Chandler, Tawny L., White, Heather M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766451/ https://www.ncbi.nlm.nih.gov/pubmed/35042927 http://dx.doi.org/10.1038/s41598-021-04755-x |
Ejemplares similares
-
Glucose metabolism is differentially altered by choline and methionine in bovine neonatal hepatocytes
por: Chandler, Tawny L., et al.
Publicado: (2019) -
Choline and methionine differentially alter methyl carbon metabolism in bovine neonatal hepatocytes
por: Chandler, Tawny L., et al.
Publicado: (2017) -
Greater liver PNPLA3 protein abundance in vivo and in vitro supports lower triglyceride accumulation in dairy cows
por: Pralle, Ryan S., et al.
Publicado: (2021) -
Fatty acid challenge shifts cellular energy metabolism in a substrate-specific manner in primary bovine neonatal hepatocytes
por: Chandler, T. L., et al.
Publicado: (2023) -
Palmitate and pyruvate carbon flux in response to choline and methionine in bovine neonatal hepatocytes
por: Chandler, T. L., et al.
Publicado: (2020)