Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble

Single-stranded DNA (ssDNA) commonly occurs as intermediates in DNA metabolic pathways. The ssDNA binding protein, RPA, not only protects the integrity of ssDNA, but also directs the downstream factor that signals or repairs the ssDNA intermediate. However, it remains unclear how these enzymes/facto...

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Detalles Bibliográficos
Autores principales: Shen, Jiangchuan, Zhao, Yiling, Pham, Nhung Tuyet, Li, Yuxi, Zhang, Yixiang, Trinidad, Jonathan, Ira, Grzegorz, Qi, Zhi, Niu, Hengyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766458/
https://www.ncbi.nlm.nih.gov/pubmed/35042867
http://dx.doi.org/10.1038/s41467-021-27940-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766458/
https://www.ncbi.nlm.nih.gov/pubmed/35042867
http://dx.doi.org/10.1038/s41467-021-27940-y

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