53BP1 regulates heterochromatin through liquid phase separation

Human 53BP1 is primarily known as a key player in regulating DNA double strand break (DSB) repair choice; however, its involvement in other biological process is less well understood. Here, we report a previously uncharacterized function of 53BP1 at heterochromatin, where it undergoes liquid-liquid...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Geng, Xinran, Wang, Fangfang, Tang, Jinshan, Ichida, Yu, Sharma, Arishya, Jin, Sora, Chen, Mingyue, Tang, Mingliang, Pozo, Franklin Mayca, Wang, Wenxiu, Wang, Janet, Wozniak, Michal, Guo, Xiaoxia, Miyagi, Masaru, Jin, Fulai, Xu, Yongjie, Yao, Xinsheng, Zhang, Youwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766474/
https://www.ncbi.nlm.nih.gov/pubmed/35042897
http://dx.doi.org/10.1038/s41467-022-28019-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766474/
https://www.ncbi.nlm.nih.gov/pubmed/35042897
http://dx.doi.org/10.1038/s41467-022-28019-y

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