Metabolic Effects of Doxorubicin on the Rat Liver Assessed With Hyperpolarized MRI and Metabolomics

Doxorubicin (DOX) is a successful chemotherapeutic widely used for the treatment of a range of cancers. However, DOX can have serious side-effects, with cardiotoxicity and hepatotoxicity being the most common events. Oxidative stress and changes in metabolism and bioenergetics are thought to be at t...

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Detalles Bibliográficos
Autores principales: Timm, Kerstin N., Ball, Vicky, Miller, Jack J., Savic, Dragana, West, James A., Griffin, Julian L., Tyler, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766499/
https://www.ncbi.nlm.nih.gov/pubmed/35069242
http://dx.doi.org/10.3389/fphys.2021.782745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766499/
https://www.ncbi.nlm.nih.gov/pubmed/35069242
http://dx.doi.org/10.3389/fphys.2021.782745

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