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Switchable deep eutectic solvent driven micellar extractive fermentation of ultrapure fibrin digesting enzyme from Bacillus subtilis

Fibrinolytic protease (FLP) is a therapeutic enzyme used in the treatment of thrombolytic diseases. The present study proposed the concept of pH-driven swappable micellar two-phase extraction for the concurrent production and purification of FLP from Bacillus subtilis at cloud point extraction. Extr...

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Detalles Bibliográficos
Autores principales: Muniasamy, Ramya, Balamurugan, Bhavani Sowndharya, Rajamahendran, Devi, Rathnasamy, Senthilkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766521/
https://www.ncbi.nlm.nih.gov/pubmed/35042908
http://dx.doi.org/10.1038/s41598-022-04788-w