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MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway

Objective: Osteoporosis is caused by the dysregulation of bone homeostasis which is synergistically mediated by osteoclasts and osteoblasts. MiR-27a-3p is a key inhibitor of bone formation. Hence, unearthing the downstream target gene of miR-27a-3p is of great significance to understand the molecula...

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Detalles Bibliográficos
Autores principales: Zeng, Zhi, Fei, Liangyu, Yang, Juntao, Zuo, Jun, Huang, Zelin, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766720/
https://www.ncbi.nlm.nih.gov/pubmed/35069685
http://dx.doi.org/10.3389/fgene.2021.783352