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MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway
Objective: Osteoporosis is caused by the dysregulation of bone homeostasis which is synergistically mediated by osteoclasts and osteoblasts. MiR-27a-3p is a key inhibitor of bone formation. Hence, unearthing the downstream target gene of miR-27a-3p is of great significance to understand the molecula...
Autores principales: | Zeng, Zhi, Fei, Liangyu, Yang, Juntao, Zuo, Jun, Huang, Zelin, Li, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766720/ https://www.ncbi.nlm.nih.gov/pubmed/35069685 http://dx.doi.org/10.3389/fgene.2021.783352 |
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