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USP14: Structure, Function, and Target Inhibition

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated with proteasomes and exerts a dual function in regulating protein degradation. USP14 protects protein substrates from degradation by removing ubiquitin chains from proteasome-bound substrates, whereas promotes pro...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Ning, Shuo, Yu, Beiming, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766727/
https://www.ncbi.nlm.nih.gov/pubmed/35069211
http://dx.doi.org/10.3389/fphar.2021.801328