Insights on Cancer Cell Inhibition, Subcellular Activities, and Kinase Profile of Phenylacetamides Pending 1H-Imidazol-5-One Variants

Structural changes of small-molecule drugs may bring interesting biological properties, especially in the field of kinase inhibitors. We sought to study tirbanibulin, a first-in-class dual Src kinase (non-ATP competitive)/tubulin inhibitor because there was not enough reporting about its structure–a...

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Detalles Bibliográficos
Autores principales: Khayat, Maan T., Omar, Abdelsattar M., Ahmed, Farid, Khan, Mohammad I., Ibrahim, Sara M., Muhammad, Yosra A., Malebari, Azizah M., Neamatallah, Thikryat, El-Araby, Moustafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766756/
https://www.ncbi.nlm.nih.gov/pubmed/35069208
http://dx.doi.org/10.3389/fphar.2021.794325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766756/
https://www.ncbi.nlm.nih.gov/pubmed/35069208
http://dx.doi.org/10.3389/fphar.2021.794325

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