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Beyond the Lesion: Back to High Fidelity DNA Synthesis

High fidelity (HiFi) DNA polymerases (Pols) perform the bulk of DNA synthesis required to duplicate genomes in all forms of life. Their structural features, enzymatic mechanisms, and inherent properties are well-described over several decades of research. HiFi Pols are so accurate that they become s...

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Detalles Bibliográficos
Autores principales: Kaszubowski, Joseph D., Trakselis, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766770/
https://www.ncbi.nlm.nih.gov/pubmed/35071328
http://dx.doi.org/10.3389/fmolb.2021.811540