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PP2A and Its Inhibitors in Helper T-Cell Differentiation and Autoimmunity

Protein phosphatase 2A (PP2A) is a highly complex heterotrimeric Ser/Thr phosphatase that regulates many cellular processes. The role of PP2A as a tumor suppressor has been extensively studied and reviewed. However, emerging evidence suggests PP2A constrains inflammatory responses and is important i...

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Detalles Bibliográficos
Autores principales: Khan, Mohd Moin, Kalim, Ubaid Ullah, Khan, Meraj H., Lahesmaa, Riitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766794/
https://www.ncbi.nlm.nih.gov/pubmed/35069561
http://dx.doi.org/10.3389/fimmu.2021.786857