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Inhibition of LRRK2-Rab10 Pathway Improves Secondary Brain Injury After Surgical Brain Injury in Rats

Leucine-rich repeat kinase 2 (LRRK2) is considered as a potential target for the treatment of Parkinson's disease. This protein is expressed in the brain and has been associated with various diseases and lysosomal maintenance. Rab10 is a member of the Rab protein GTPase family that has been rec...

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Detalles Bibliográficos
Autores principales: Li, Jie, Wu, Muyao, Gong, Yating, Tang, Jiafeng, Shen, Jinchao, Xu, Li, Dang, Baoqi, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766807/
https://www.ncbi.nlm.nih.gov/pubmed/35071308
http://dx.doi.org/10.3389/fsurg.2021.749310