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Enhanced Proinflammatory Cytokine Production and Immunometabolic Impairment of NK Cells Exposed to Mycobacterium tuberculosis and Cigarette Smoke

AIM: Smoker COPD patients with chest radiological signs of prior tuberculosis (TB) showed more severe lung damage, but the mechanisms remain unclear. Emerging evidence has implicated NK cells in the pathogenesis of both COPD and TB. The purpose of this study was to delineate the profile and cytokine...

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Detalles Bibliográficos
Autores principales: Rao, Yafei, Gai, Xiaoyan, Le, Yanqing, Xiong, Jing, Liu, Yujia, Zhang, Xueyang, Wang, Jundong, Cao, Wenli, Sun, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766853/
https://www.ncbi.nlm.nih.gov/pubmed/35071048
http://dx.doi.org/10.3389/fcimb.2021.799276