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In vivo deep network tracing reveals phosphofructokinase-mediated coordination of biosynthetic pathway activity in the myocardium

Glucose metabolism comprises numerous amphibolic metabolites that provide precursors for not only the synthesis of cellular building blocks but also for ATP production. In this study, we tested how phosphofructokinase-1 (PFK1) activity controls the fate of glucose-derived carbon in murine hearts in...

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Detalles Bibliográficos
Autores principales: Fulghum, Kyle L., Audam, Timothy N., Lorkiewicz, Pawel K., Zheng, Yuting, Merchant, Michael, Cummins, Timothy D., Dean, William L., Cassel, Teresa A., Fan, Teresa W. M., Hill, Bradford G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766935/
https://www.ncbi.nlm.nih.gov/pubmed/34487754
http://dx.doi.org/10.1016/j.yjmcc.2021.08.013