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Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: a double-blind, randomized, placebo-controlled multi-center clinical trial

This study tested the efficacy of repeated intravenous ketamine doses to reduce symptoms of posttraumatic stress disorder (PTSD). Veterans and service members with PTSD (n = 158) who failed previous antidepressant treatment were randomized to 8 infusions administered twice weekly of intravenous plac...

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Detalles Bibliográficos
Autores principales: Abdallah, Chadi G., Roache, John D., Gueorguieva, Ralitza, Averill, Lynnette A., Young-McCaughan, Stacey, Shiroma, Paulo R., Purohit, Prerana, Brundige, Antoinette, Murff, William, Ahn, Kyung-Heup, Sherif, Mohamed A., Baltutis, Eric J., Ranganathan, Mohini, D’Souza, Deepak, Martini, Brenda, Southwick, Steven M., Petrakis, Ismene L., Burson, Rebecca R., Guthmiller, Kevin B., López-Roca, Argelio L., Lautenschlager, Karl A., McCallin, John P., Hoch, Matthew B., Timchenko, Alexandar, Souza, Sergio E., Bryant, Charles E., Mintz, Jim, Litz, Brett T., Williamson, Douglas E., Keane, Terence M., Peterson, Alan L., Krystal, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767037/
https://www.ncbi.nlm.nih.gov/pubmed/35046508
http://dx.doi.org/10.1038/s41386-022-01266-9