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The Priming Potential of Interferon Lambda-1 for Antiviral Defense in the Oral Mucosa

The oral mucosa is one of the first lines of the innate host defense system against microbial invasion. Interferon (IFN) lambda-1 (IFN-λ1), a type III IFN, exhibits type I IFN-like antiviral activity. In contrast to ubiquitously expressed type I IFN receptors, IFN-λ receptor 1 (IFN-λR1), which has h...

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Detalles Bibliográficos
Autores principales: Shikama, Yosuke, Kurosawa, Mie, Furukawa, Masae, Kudo, Yasusei, Ishimaru, Naozumi, Matsushita, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767043/
https://www.ncbi.nlm.nih.gov/pubmed/35044570
http://dx.doi.org/10.1007/s10753-022-01624-1