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Myeloid Fbxw7 Prevents Pulmonary Fibrosis by Suppressing TGF-β Production

Idiopathic pulmonary fibrosis (IPF) is a group of chronic interstitial pulmonary diseases characterized by an inexorable decline in lung function with limited treatment options. The abnormal expression of transforming growth factor-β (TGF-β) in profibrotic macrophages is linked to severe pulmonary f...

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Detalles Bibliográficos
Autores principales: He, Jia, Du, Yue, Li, Gaopeng, Xiao, Peng, Sun, Xingzheng, Song, Wenjun, Lai, Lihua, Xia, Meng, Zhang, Jianhua, Wang, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767095/
https://www.ncbi.nlm.nih.gov/pubmed/35069531
http://dx.doi.org/10.3389/fimmu.2021.760138