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Cleavage-Mediated Regulation of Myd88 Signaling by Inflammasome-Activated Caspase-1

Coordination among multiple signaling pathways ensures an appropriate immune response, where a signaling pathway may impair or augment another signaling pathway. Here, we report a negative feedback regulation of signaling through the key innate immune mediator MyD88 by inflammasome-activated caspase...

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Detalles Bibliográficos
Autores principales: Avbelj, Monika, Hafner-Bratkovič, Iva, Lainšček, Duško, Manček-Keber, Mateja, Peternelj, Tina Tinkara, Panter, Gabriela, Treon, Steven P., Gole, Boris, Potočnik, Uroš, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767097/
https://www.ncbi.nlm.nih.gov/pubmed/35069570
http://dx.doi.org/10.3389/fimmu.2021.790258