Cargando…

CXCR4 Mediates Enhanced Cell Migration in CALM-AF10 Leukemia

Leukemia transformed by the CALM-AF10 chromosomal translocation is characterized by a high incidence of extramedullary disease, central nervous system (CNS) relapse, and a poor prognosis. Invasion of the extramedullary compartment and CNS requires leukemia cell migration out of the marrow and adhere...

Descripción completa

Detalles Bibliográficos
Autores principales: Fertal, Shelby A., Zaidi, Sayyed K., Stein, Janet L., Stein, Gary S., Heath, Jessica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767107/
https://www.ncbi.nlm.nih.gov/pubmed/35070954
http://dx.doi.org/10.3389/fonc.2021.708915