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A Phase 2 Trial Combining Pembrolizumab and Palliative Radiation Therapy in Gastroesophageal Cancer to Augment Abscopal Immune Responses

PURPOSE: Single agent PD-1 inhibitors have yielded durable responses in a minority of gastroesophageal cancers. Radiation therapy has been recognized to promote antitumor immune responses and may synergize with anti-PD-1 agents. We sought to evaluate if combining palliative radiation therapy with pe...

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Detalles Bibliográficos
Autores principales: Chao, Joseph, He, Ting-Fang, D'Apuzzo, Massimo, Chen, Yi-Jen, Frankel, Paul, Tajon, Michael, Chen, Helen, Solomon, Shawn, Klempner, Samuel J., Fakih, Marwan, Lee, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767243/
https://www.ncbi.nlm.nih.gov/pubmed/35071830
http://dx.doi.org/10.1016/j.adro.2021.100807