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Inhibition of minor intron splicing reduces Na(+) and Ca(2+) channel expression and function in cardiomyocytes
Eukaryotic genomes contain a tiny subset of ‘minor class’ introns with unique sequence elements that require their own splicing machinery. These minor introns are present in certain gene families with specific functions, such as voltage-gated Na(+) and voltage-gated Ca(2+) channels. Removal of minor...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767276/ https://www.ncbi.nlm.nih.gov/pubmed/34859816 http://dx.doi.org/10.1242/jcs.259191 |