Whole genome sequencing reveals large deletions and other loss of function mutations in Mycobacterium tuberculosis drug resistance genes

Drug resistance in Mycobacterium tuberculosis , the causative agent of tuberculosis disease, arises from genetic mutations in genes coding for drug-targets or drug-converting enzymes. SNPs linked to drug resistance have been extensively studied and form the basis of molecular diagnostics and sequenc...

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Detalles Bibliográficos
Autores principales: Gomes, Laura C., Campino, Susana, Marinho, Cláudio R. F., Clark, Taane G., Phelan, Jody E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767347/
https://www.ncbi.nlm.nih.gov/pubmed/34889724
http://dx.doi.org/10.1099/mgen.0.000724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767347/
https://www.ncbi.nlm.nih.gov/pubmed/34889724
http://dx.doi.org/10.1099/mgen.0.000724

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