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Frequency of Adverse Events in the Placebo Arms of COVID-19 Vaccine Trials: A Systematic Review and Meta-analysis

IMPORTANCE: Adverse events (AEs) after placebo treatment are common in randomized clinical drug trials. Systematic evidence regarding these nocebo responses in vaccine trials is important for COVID-19 vaccination worldwide especially because concern about AEs is reported to be a reason for vaccinati...

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Detalles Bibliográficos
Autores principales: Haas, Julia W., Bender, Friederike L., Ballou, Sarah, Kelley, John M., Wilhelm, Marcel, Miller, Franklin G., Rief, Winfried, Kaptchuk, Ted J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767431/
https://www.ncbi.nlm.nih.gov/pubmed/35040967
http://dx.doi.org/10.1001/jamanetworkopen.2021.43955