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Inhibition of FOXO1-mediated autophagy promotes paclitaxel-induced apoptosis of MDA-MB-231 cells

Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, and it often becomes resistant to paclitaxel (PTX) therapy. Autophagy plays an important cytoprotective role in PTX-induced tumor cell death, and targeting autophagy has been promising for improving the efficacy of...

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Detalles Bibliográficos
Autores principales: Xu, Kaixiang, Zhu, Wanyun, Xu, Anyong, Xiong, Zhe, Zou, Di, Zhao, Heng, Jiao, Deling, Qing, Yubo, Jamal, Muhammad Ameen, Wei, Hong-Jiang, Zhao, Hong-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767459/
https://www.ncbi.nlm.nih.gov/pubmed/35014689
http://dx.doi.org/10.3892/mmr.2022.12588