Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies

Human health risks from chronic exposures to environmental chemicals are typically estimated from potential human exposure estimates and dose-response data obtained from repeated-dose animal toxicity studies. Various criteria are available for selecting the top (highest) dose used in these animal st...

Descripción completa

Detalles Bibliográficos
Autores principales: Lowe, Kelly, Dawson, Jeffrey, Phillips, Katherine, Minucci, Jeffrey, Wambaugh, John F., Qian, Hua, Ramanarayanan, Tharacad, Egeghy, Peter, Ingle, Brandall, Brunner, Rachel, Mendez, Elizabeth, Embry, Michelle, Tan, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767482/
https://www.ncbi.nlm.nih.gov/pubmed/34743952
http://dx.doi.org/10.1016/j.yrtph.2021.105073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767482/
https://www.ncbi.nlm.nih.gov/pubmed/34743952
http://dx.doi.org/10.1016/j.yrtph.2021.105073

Ejemplares similares