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Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies
Human health risks from chronic exposures to environmental chemicals are typically estimated from potential human exposure estimates and dose-response data obtained from repeated-dose animal toxicity studies. Various criteria are available for selecting the top (highest) dose used in these animal st...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767482/ https://www.ncbi.nlm.nih.gov/pubmed/34743952 http://dx.doi.org/10.1016/j.yrtph.2021.105073 |