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Chemical and chemoenzymatic routes to bridged homoarabinofuranosylpyrimidines: Bicyclic AZT analogues

Conformationally restricted diastereomeric homoarabinofuranosylpyrimidines (AZT analogue), i.e., (5′R)-3′-azido-3′-deoxy-2′-O,5′-C-bridged-β-ᴅ-homoarabinofuranosylthymine and -uracil had been synthesized starting from diacetone ᴅ-glucofuranose following chemoenzymatic and chemical routes in 34–35% a...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Maity, Jyotirmoy, Kumar, Banty, Kumar, Sumit, Prasad, Ashok K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767562/
https://www.ncbi.nlm.nih.gov/pubmed/35096178
http://dx.doi.org/10.3762/bjoc.18.10