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Differential immunogenicity of homologous versus heterologous boost in Ad26.COV2.S vaccine recipients

BACKGROUND: Protection offered by coronavirus disease 2019 (COVID-19) vaccines wanes over time, requiring an evaluation of different boosting strategies to revert such a trend and enhance the quantity and quality of Spike-specific humoral and cellular immune responses. These immunological parameters...

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Detalles Bibliográficos
Autores principales: Khoo, Nicholas Kim Huat, Lim, Joey Ming Er, Gill, Upkar S., de Alwis, Ruklanthi, Tan, Nicole, Toh, Justin Zhen Nan, Abbott, Jane E., Usai, Carla, Ooi, Eng Eong, Low, Jenny Guek Hong, Le Bert, Nina, Kennedy, Patrick T.F., Bertoletti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8767655/
https://www.ncbi.nlm.nih.gov/pubmed/35072129
http://dx.doi.org/10.1016/j.medj.2021.12.004