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KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity

Influenza A virus (IAV) RNA-dependent RNA polymerase (vPol) is a heterotrimer composed of PB2, PB1, and PA, which, together with vRNA and nucleoprotein (NP), forms viral ribonucleoprotein (vRNP) complex to direct the transcription and replication of the viral genome. Host factor ANP32 proteins have...

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Detalles Bibliográficos
Autores principales: Yu, Mengmeng, Sun, Liuke, Zhang, Zhenyu, Zhang, Yuan, Zhang, Haili, Na, Lei, Wang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768627/
https://www.ncbi.nlm.nih.gov/pubmed/35044222
http://dx.doi.org/10.1128/spectrum.02073-21