Tunable heteroaromatic azoline thioethers (HATs) for cysteine profiling

Here we report a new series of hydrolytically stable chemotype heteroaromatic azoline thioethers (HATs) to achieve highly selective, rapid, and efficient covalent labeling of cysteine under physiological conditions. Although the resulting cysteine–azoline conjugate is stable, we highlight traceless...

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Detalles Bibliográficos
Autores principales: Tang, Kuei C., Maddox, Sean M., Backus, Keriann M., Raj, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768877/
https://www.ncbi.nlm.nih.gov/pubmed/35173941
http://dx.doi.org/10.1039/d1sc04139h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768877/
https://www.ncbi.nlm.nih.gov/pubmed/35173941
http://dx.doi.org/10.1039/d1sc04139h

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