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Ring-opening fluorination of bicyclic azaarenes

We have discovered a ring-opening fluorination of bicyclic azaarenes. Upon treatment of bicyclic azaarenes such as pyrazolo[1,5-a]pyridines with electrophilic fluorinating agents, fluorination of the aromatic ring is followed by a ring-opening reaction. Although this overall transformation can be cl...

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Detalles Bibliográficos
Autores principales: Komatsuda, Masaaki, Suto, Ayane, Kondo, Hiroki, Takada, Hiroyuki, Kato, Kenta, Saito, Bunnai, Yamaguchi, Junichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8768879/
https://www.ncbi.nlm.nih.gov/pubmed/35173930
http://dx.doi.org/10.1039/d1sc06273e