Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems

After oral administration, a drug’s solubility in intestinal fluid is an important parameter influencing bioavailability and if the value is known it can be applied to estimate multiple biopharmaceutical parameters including the solubility limited absorbable dose. Current in vitro measurements may u...

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Detalles Bibliográficos
Autores principales: Abuhassan, Qamar, Khadra, Ibrahim, Pyper, Kate, Augustijns, Patrick, Brouwers, Joachim, Halbert, Gavin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769049/
https://www.ncbi.nlm.nih.gov/pubmed/34923138
http://dx.doi.org/10.1016/j.ejpb.2021.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769049/
https://www.ncbi.nlm.nih.gov/pubmed/34923138
http://dx.doi.org/10.1016/j.ejpb.2021.12.006

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