Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies

Botulinum neurotoxins (BoNTs) are among the deadliest of bacterial toxins. BoNT serotype A and B in particular pose the most serious threat to humans because of their high potency and persistence. To date, there is no effective treatment for late post-exposure therapy of botulism patients. Here, we...

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Detalles Bibliográficos
Autores principales: Lam, Kwok-ho, Tremblay, Jacqueline M., Perry, Kay, Ichtchenko, Konstantin, Shoemaker, Charles B., Jin, Rongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769338/
https://www.ncbi.nlm.nih.gov/pubmed/34990480
http://dx.doi.org/10.1371/journal.ppat.1010169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769338/
https://www.ncbi.nlm.nih.gov/pubmed/34990480
http://dx.doi.org/10.1371/journal.ppat.1010169

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