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Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies
Botulinum neurotoxins (BoNTs) are among the deadliest of bacterial toxins. BoNT serotype A and B in particular pose the most serious threat to humans because of their high potency and persistence. To date, there is no effective treatment for late post-exposure therapy of botulism patients. Here, we...
Autores principales: | Lam, Kwok-ho, Tremblay, Jacqueline M., Perry, Kay, Ichtchenko, Konstantin, Shoemaker, Charles B., Jin, Rongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769338/ https://www.ncbi.nlm.nih.gov/pubmed/34990480 http://dx.doi.org/10.1371/journal.ppat.1010169 |
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