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Differential gene expression analysis identified determinants of cell fate plasticity during radiation-induced regeneration in Drosophila

Ionizing radiation (IR) is used to treat half of all cancer patients because of its ability to kill cells. IR, however, can induce stem cell-like properties in non-stem cancer cells, potentiating tumor regrowth and reduced therapeutic success. We identified previously a subpopulation of cells in Dro...

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Detalles Bibliográficos
Autores principales: Ledru, Michelle, Clark, Caitlin A., Brown, Jeremy, Verghese, Shilpi, Ferrara, Sarah, Goodspeed, Andrew, Su, Tin Tin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769364/
https://www.ncbi.nlm.nih.gov/pubmed/34990447
http://dx.doi.org/10.1371/journal.pgen.1009989