Genetic Characteristics of Mismatch Repair-deficient Glioblastoma

Mismatch repair (MMR) gene deficiency is rarely observed in gliomas, a constitutional defect is associated with tumorigenesis in Lynch syndrome, and an acquired defect is associated with hypermutation after temozolomide treatment. However, the meaning of MMR gene deficiency in gliomas is unclear. Tw...

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Detalles Bibliográficos
Autores principales: KAWAGUCHI, Kei, OTANI, Ryohei, KIKUCHI, Miyu, KUSHIHARA, Yoshihiro, FUNATA, Nobuaki, YAMADA, Ryoji, SHINOURA, Nobusada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769403/
https://www.ncbi.nlm.nih.gov/pubmed/35079518
http://dx.doi.org/10.2176/nmccrj.cr.2020-0366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769403/
https://www.ncbi.nlm.nih.gov/pubmed/35079518
http://dx.doi.org/10.2176/nmccrj.cr.2020-0366

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