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Genetic Characteristics of Mismatch Repair-deficient Glioblastoma
Mismatch repair (MMR) gene deficiency is rarely observed in gliomas, a constitutional defect is associated with tumorigenesis in Lynch syndrome, and an acquired defect is associated with hypermutation after temozolomide treatment. However, the meaning of MMR gene deficiency in gliomas is unclear. Tw...
Autores principales: | KAWAGUCHI, Kei, OTANI, Ryohei, KIKUCHI, Miyu, KUSHIHARA, Yoshihiro, FUNATA, Nobuaki, YAMADA, Ryoji, SHINOURA, Nobusada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japan Neurosurgical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769403/ https://www.ncbi.nlm.nih.gov/pubmed/35079518 http://dx.doi.org/10.2176/nmccrj.cr.2020-0366 |
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