Cargando…

Widespread occurrence of hybrid internal-terminal exons in human transcriptomes

Messenger RNA isoform differences are predominantly driven by alternative first, internal, and last exons. Despite the importance of classifying exons to understand isoform structure, few tools examine isoform-specific exon usage. We recently observed that alternative transcription start sites often...

Descripción completa

Detalles Bibliográficos
Autores principales: Fiszbein, Ana, McGurk, Michael, Calvo-Roitberg, Ezequiel, Kim, GyeungYun, Burge, Christopher B., Pai, Athma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769537/
https://www.ncbi.nlm.nih.gov/pubmed/35044812
http://dx.doi.org/10.1126/sciadv.abk1752