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The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

The processes of genome replication and transcription of SARS-CoV-2 represent important targets for viral inhibition. Betacoronaviral nucleoprotein (N) is a highly dynamic cofactor of the replication-transcription complex (RTC), whose function depends on an essential interaction with the amino-termi...

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Detalles Bibliográficos
Autores principales: Bessa, Luiza Mamigonian, Guseva, Serafima, Camacho-Zarco, Aldo R., Salvi, Nicola, Maurin, Damien, Perez, Laura Mariño, Botova, Maiia, Malki, Anas, Nanao, Max, Jensen, Malene Ringkjøbing, Ruigrok, Rob W. H., Blackledge, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769549/
https://www.ncbi.nlm.nih.gov/pubmed/35044811
http://dx.doi.org/10.1126/sciadv.abm4034