Cargando…

Recapitulating hepatitis E virus–host interactions and facilitating antiviral drug discovery in human liver–derived organoids

Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the development of robust experimental models. The advent of organoid technology provides a unique opportunity for moving the field forward. Here, we demonstrate that three-dimensional cultured organoids from fetal and...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Pengfei, Li, Yunlong, Wang, Yijin, Liu, Jiaye, Lavrijsen, Marla, Li, Yang, Zhang, Ruyi, Verstegen, Monique M. A., Wang, Yining, Li, Tian-Cheng, Ma, Zhongren, Kainov, Denis E., Bruno, Marco J., de Man, Robert A., van der Laan, Luc J. W., Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769558/
https://www.ncbi.nlm.nih.gov/pubmed/35044825
http://dx.doi.org/10.1126/sciadv.abj5908