Recapitulating hepatitis E virus–host interactions and facilitating antiviral drug discovery in human liver–derived organoids

Hepatotropic viruses naturally have narrow host and tissue tropisms, challenging the development of robust experimental models. The advent of organoid technology provides a unique opportunity for moving the field forward. Here, we demonstrate that three-dimensional cultured organoids from fetal and...

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Detalles Bibliográficos
Autores principales: Li, Pengfei, Li, Yunlong, Wang, Yijin, Liu, Jiaye, Lavrijsen, Marla, Li, Yang, Zhang, Ruyi, Verstegen, Monique M. A., Wang, Yining, Li, Tian-Cheng, Ma, Zhongren, Kainov, Denis E., Bruno, Marco J., de Man, Robert A., van der Laan, Luc J. W., Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769558/
https://www.ncbi.nlm.nih.gov/pubmed/35044825
http://dx.doi.org/10.1126/sciadv.abj5908

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